What is Foundayo?

Foundayo® (Orforglipron) Weight Loss Tablets. A once-daily GLP-1 tablet that helps regulate appetite, helping you eat less and support your weight loss journey. Taken at any time of day, with or without food, offering a flexible alternative for those who would prefer a tablet to injections. Tailored to your individual needs and overseen by experienced clinicians for your safety. Full access to your client portal alongside progress tracking tools.

Dosage

Foundayo is available in 6 strengths: 0.8, 2.5, 5.5, 9, 14.5, 17.2mg.

The usual starting dose is 0.8mg once daily for 30 days, followed by 2.5mg once daily. Your clinician may then gradually increase your dose depending on your treatment response and how well you tolerate the medication. The maximum dose is 17.2mg once daily.

How does Foundayo work?

Foundayo contains the active ingredient orforglipron, a GLP-1 receptor agonist. It works by influencing the way your body regulates appetite, which can help you feel satisfied with less food and support weight loss when used alongside a reduced-calorie diet and increased physical activity.

How do I take Foundayo?

Foundayo is taken as one tablet once a day. Unlike some other oral GLP-1 treatments, Foundayo can be taken at any time of day, with or without food.

Swallow the tablet whole. Do not break, crush or chew it. Try to build taking your tablet into your daily routine to help you remember it each day.

If you forget your Foundayo tablet, take it as soon as you remember. Do not take more than one dose in the same day and do not take a double dose to make up for one you've missed.

What are the side effects?

Very common side effects, affecting more than 1 in 10 people, include:

  • Nausea
  • Constipation
  • Diarrhoea
  • Vomiting
  • Indigestion
  • Abdominal pain

Nausea, diarrhoea and vomiting are most common when first starting treatment and decrease over time for most patients. Other common side effects can include headache, dizziness, bloating, burping, heartburn, gas, gallstones, hair loss and tiredness. Speak to your clinical team if you're concerned about any side effects or if they're difficult to manage.

Who can use Foundayo for weight management?

Foundayo is licensed for weight management alongside a reduced-calorie diet and increased physical activity in adults who initially have a BMI of 30 or above, or a BMI of at least 27 but below 30, together with at least one weight-related health condition.

Your BMI alone doesn't determine whether treatment is suitable. Your clinician will review your complete medical information before making a prescribing decision.

Clinical monitoring

Foundayo has been authorised by the MHRA for weight management in appropriate adults. Your consultation will be reviewed by a qualified prescriber before treatment is prescribed, and ongoing check-ins help us monitor your progress throughout treatment. Foundayo is also currently subject to additional safety monitoring in the UK.

Safe use of Foundayo:

We provide a full safety and information pack with your medication. We recommend that you read this thoroughly prior to taking any medication, and always read the Patient Information Leaflet supplied with your medication.